THE PERPETUATION OF A LEGEND
XP 1 – R&D Single Punch Press
The XP 1 research tablet press is the successor of the legendary EK 0. This single punch machine is specifically designed to permit initial feasibility, screening, and solid product characterization. The XP 1 permits very small material quantities to be utilized and characterized very quickly with a minimum of set-up and cleaning time. The XP 1 offers a proven, rugged, and portable design, which insures precision operation over the long term.
SINGLE PUNCH PRESS
DEVELOPMENT WITH MINIMAL MATERIAL QUANTITIES
MAX. 50 kN
FULL INSTRUMENTATION AND DATA ANALYSIS
Designed for Pharma & Nutraceuticals
The complete separation of the product area from the mechanical area guarantees a GMP compliant working environment. The machine complies all valid FDA-regulations. KORSCH controls permit full compliance with 21 CFR Part 11.
The XP 1 is offered in a “table-top”space efficient execution or optionally as a portable execution with a full stainless steel lower cabinet with locking caster base.
Flexible Operation: From Small to Larger Material Quantities
The single punch press is suitable for both small and larger press material quantities, in both cases with a minimum of set-up and cleaning time:
- Feeder for 5 liters or for small material quantities (8 ml)
- Different Material Hopper configurations from 5 liters to very small quantities
Use of Standard Press Tools
Use of standard TSM B/D or EU B/D and EK 0 tooling. An innovative tool adaptor permits the fast change of press tooling.
The XP 1 can work with a wide range of tablet formats, including microtablets to a maximum tablet diameter of 25 mm.
Full Accessibility and Easy Cleaning
The compression zone on the XP 1 is fully accessible. The complete drive system for the press is mounted behind the back wall, so that the compression zone is clean and all components are easily removed and re-installed. The open design and the smooth surface as well as the separation of the product area from the technical area enable easy and fast cleaning.
Control with Operating Panel
A user friendly Siemens touch screen permits the adjustment of press speed and offers the real-time display of compression and ejection force.
Calibrated hand wheel adjustments for upper punch insertion depth and filling depth permit the tablet weight, thickness, and hardness to be adjusted even while the machine is running.
Instrumentation and Data Analysis
A full instrumentation package allows precision measurement of upper/lower compression force, ejection and scrape off force and upper/lower punch displacement. Together with the KORSCH PharmaResearch, the XP 1 offers a comprehensive acquisition and analysis of press force and punch displacement.
KORSCH offers a wide range of containment solutions on most machine models, including DryCon and WipCon® executions. With proven solutions across the full containment range (OEB 3, OEB 4, OEB 5), KORSCH provides a fully turnkey system which is engineered to meet the specific requirements of the project. In partnership with the customer, KORSCH specialists define critical process parameters, including containment requirements, peripheral integration, and automation design. KORSCH engineers are expert in developing the concept, execution, integration, and final SMEPAC testing to fully validate the containment capability.
XP 1 WipCon®
The XP 1 WipCon® addresses all aspects of operator safety in a contained R&D press and permits extreme flexibility for feasibility, development, and material characterization. The WipCon® design eliminates the need for personnel protection equipment (PPE). The use of a standard RTP permits granulation and finished tablets to be passed in and out of the machine isolator in a fully contained manner.