Ideal for limited amount of material
Tableting has never been so easy to investigate, from pure API characterization to formulation assessment. The STYL’One Nano includes in a small footprint the unique and powerful drive technology, normally reserved for an Elite of premium compaction simulators. Scientists can use the flexibility to drive the punches at high velocity to replicate the pre and main compression of an R&D rotary tablet press. The powerful Alix data acquisition and analysis software allows to screen a formulation in less than 5 minutes.
SINGLE PUNCH PRESS
MAX. 50 KN
FULL INSTRUMENTATION & DATA ANALYSIS
Designed for Pharma & Nutraceuticals
The STYL’One Nano is a compact tabletop unit that is easy to clean due to a GMP working area featuring smooth surfaces and full accessibility. It permits very small material quantities to be utilized and characterized very quickly with a minimum of set-up. With a range of options and accessories the STYL’One Nano is a flexible research tool.
The STYL’One Nano covers the following fields of applicaton:
- API / Excipient characterization: work with minimal material quantities to assess material attributes and compare different material suppliers
- Analytical development: sample production for analytical method development and validation
- Formulation feasibility and optimization: evaluate effect of Process Parameters (PP), assess Quality Attributes (QA) or produce early stability batches
The STYL'One Nano is designed with the most advanced instrumentation to measure the upper and lower compression force and punch position. Mechanical deformation is automatically measured and compensated for by the software
- Precompression Force
- Main Compression Force
- Ejection Force
- Upper Punch Displacement
- Lower Punch Displacement
Powerful data acquisition and analysis software
The software Alix controls the STYL’One Nano, collects the data generated and analyzes the data by plotting a wide range of parameters including manufacturability, tabletability, compressibility and compactibility. Customized plots for any data parameter are easily developed. The HMI interface simplifies the design and execution of experiments. Tablet tester data can be uploaded and graphs generated.
The machine permits the use of standard TSM / EU B, BB, BBS and D tooling of any shapes, including multi-tip and oversized tooling. The STYL’One Nano permits a wide range of tablet formats, including mini-tablets of 2 mm to a maximum tablet diameter of 40 mm.
- Simple tool setup and exchange
- Minimal parts to assemble
- Change over in 5 minutes
- Up to 40 mm diameter oversized tooling
With a wide range of filling options, the STYL’One Nano is a flexible research tool that can easily be adapted to the amount and type of product to be processed.
- Manual Filling: only a few grams of material
- Gravity feeder: low amount of material
- Force feeder: challenging formulation and/or mini-tablets
Simulation of R&D rotary tablet press
At the heart of the STYL’One is a powerful drive system controlled by the Alix software, which supports high punch acceleration and velocity required to mimic R&D rotary press kinetics. The STYL’One Nano features up to 50 kN precompression and main compression capability. The possibility to apply a precompression allows testing its impact on formulation. The machine allows the simulation of R&D rotary tablet presses with different compression profiles, like V-shape or extended dwell time.
The STYL’One Nano can be setup in less than 5 minutes. Due to the streamlined design of the compression zone only a limited number of components need to be removed ensuring a higher level of serviceability. The working area permits a fast and easy cleaning. All optional accessories are just as easy to install.